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Mailing address:
Department of
Environmental and
Molecular Toxicology
Box 7633, NC State University
Raleigh, NC 27695-7633


Shipping address:
Suite 1104, 850 Main Campus Dr.
Raleigh, NC 27606


Phone 919.515.2274
Fax 919.515.7169

Directions to the Toxicology Building



Welcome to the Department of Environmental & Molecular Toxicology website!

The science of toxicology is anchored in the societal need to evaluate exposure, hazard, and risk associated with toxic materials. NC State University has propelled toxicology beyond its traditional boundaries by applying the most advanced technologies to assess normal structure and function at all levels of biological organization. This knowledge then is used to evaluate impacts of current and emerging environmental contaminants and other stressors. Areas of research excellence within the Department span a vast array of training opportunities including: elucidating the relationships among cell signaling processes and disease, establishing mechanisms of system-specific toxicity, using physiological and genomic approaches to understand differences in species and individual susceptibility to environmental contaminants, and unraveling environment-gene interactions.

The Department is located on the University's technology-based Centennial Campus. Centennial Campus is the national model for a successful university research park, having been named the top Research Science Park of 2007 by the Association of University Research Parks. Centennial Campus houses more than 130 companies, government agencies, and NC State research and academic units advancing technologies ranging from nanomaterials to advanced genomic analyses. Partnerships between NC State and non-university entities located in the park provide for cutting-edge research and training opportunities.

Based on a strong history and foundation of research funding from the National Institutes of Health, graduate degrees in toxicology were first awarded at NC State University in 1979. Today, the Department is home to 16 core faculty members, 18 associate faculty members, and 23 adjunct faculty members. Adjunct faculty members provide training opportunities and other linkages to neighboring institutions, including the National Institute of Environmental Health Sciences (NIEHS), the US Environmental Protection Agency (USEPA), the US Geological Survey, the Hamner Institutes for Health Sciences, GlaxoSmithKline, and Bayer Crop Science.

Graduate Programs leading to masters (MTOX and MS) and doctoral degrees (Ph.D.) in General Toxicology or with a concentration in Molecular and Cellular Toxicology or Environmental Toxicology provide students the opportunity to focus their research and to pursue study that will prepare them for a range of career paths. Students are awarded traineeships through various sources, including an NIEHS training grant and a USEPA cooperative training agreement. PhD students have the opportunity to rotate in several laboratories during their first semester before selecting a permanent training laboratory and mentor. Students are provided a generous stipend and participate in the Graduate Student Support Plan which covers tuition, fees, and health insurance. Unique to a handful of universities, the Toxicology Extension program provides a venue for students to address current trends and emerging issues in human health risk and environmental quality through its outreach programs in Agromedicine, Environmental Toxicology, General Toxicology, and Pesticides.

The Department of Environmental & Molecular Toxicology continues to define graduate training in toxicology. Graduates of our program are primed for leadership roles in academia, government, and industry. Our alumni are a testament to the Department's success in graduating individuals who have the training, talent, and confidence required for success in their chosen career. Please tour our website to gain a full appreciation of the research, academic, and extension activities of the Department.

History of Toxicology at NC State University

1964 NIH Program Grant awarded; continuously funded for 32 years
1964 Interdepartmental Program in Toxicology at NCSU established
1965 NIH Training Grant awarded; one of the longest continuously funded
NIEHS training grants in the country
1979 Responsibility for graduate degrees in toxicology awarded (Master of
Toxicology, Master of Science, and Doctor of Philosophy)
1979 First PhD in toxicology granted
1980 Introduction to Biochemical Toxicology , 1st edition, edited by Ernest Hodgson and Frank Guthrie, published by Elsevier. Now in 4th edition, edited by Robert Smart and Ernest Hodgson (in press, 2008, John Wiley and Sons).
1986 First toxicology faculty member, Dr. Robert Smart, hired into the Toxicology Program
1987 A Textbook of Modern Toxicology, edited by Ernest Hodgson and Pat Levi, published by Elsevier. Now in 3rd edition, edited by Ernest Hodgson, published 2004 by John Wiley and Sons.
1989 Dr. Gerald LeBlanc joins faculty
1989 Department of Toxicology established;
founding core faculty include Drs. Walter Dauterman, Ernest Hodgson, Frank Guthrie, Gerald LeBlanc, Ross Leidy, Patricia Levi, Jack Sheets and Robert Smart;
founding associate faculty include Drs. K. Adler, A. Aronson, C. Brownie, C.F. Brownie, R. Cattley, J. Cullen, W. Donaldson, D. Grosch, P. Hamilton, H. Hassan, D. Hayne, W. Heck, R. Kuhr, R. Linderman, W. McKenzie, R. Monroe, N. Monteiro-Riviere, D. Moreland, M. Qureshi, J. Riviere, C. Robinette;
founding adjunct faculty include: M. Anderson, N. Chernoff, T. Eling, J. Fouts, P. James, J. Goldstein, R. Langenbach, H. Matthews, R. Philpot, B. Schwetz, R Yang
1990 Degrees awarded to date: PhD: 44, MS: 16; MTOX: 2
1990 Dr. Mary Beth Genter joins faculty; Extension program in toxicology established
1992 Dr. Sharon Meyer joins faculty
1993 Drs. Damian Shea and Randy Rose join faculty
1994 Julia Storm joins Extension faculty
1995 Dr. Stacy Branch joins faculty
1997 Dr. Greg Cope joins faculty
1997 Dr. Gary Winston appointed Department Head
1998 EPA Cooperative Training in Environmental Sciences Research grant funded
1999 Dr. Hosni Hassan appointed Interim Department Head
2000 Degrees awarded to date: PhD: 98, MS: 29; MTOX: 7
2000 Graduate study concentrations in Environmental Toxicology and Molecular and Cellular Toxicology offered
2000 Name changed to Department of Environmental and Molecular Toxicology
2000 Dr. Patricia McClellan-Green joins faculty
2000 Groundbreaking of Toxicology Building on Centennial Campus
2001 Toxicology Building on Centennial Campus opens
2001 Dr. Yoshi Tsuji joins faculty
2002 Dr. Damian Shea appointed Department Head
2002 Drs. Chris Hofelt, Jun Ninomiya-Tsuji and Marjorie Oleksiak join faculty
2003 Undergraduate minor in environmental toxicology established
2003 Dr. Andrew Wallace joins faculty
2003 Dr. Ernest Hodgson, Founding Department Head, retires
2004 First undergraduate minor in environmental toxicology awarded
2005 Metabolomics and Proteomics Laboratory established; Dr. Nigel Deighton appointed Director
2005 Dr. David Buchwalter joins faculty
2007 Randy L. Rose Memorial Symposium held to honor Rose's life and contribution to science
2007 Drs. James Bonner, Seth Kullman and Scott McCulloch join the faculty
2008 Degrees awarded to date: PhD: 142, MS: 38; MTOX: 25
2008 Dr. Gerald LeBlanc appointed Department Head
2008 Genome Research Laboratory and Metabolomics and Proteomics Laboratory merged to form Genomic Sciences Laboratory; Dr. Nigel Deighton appointed Director